Primary Identifier | MGI:3530739 | Allele Type | Spontaneous |
Gene | Zbtb7b | Inheritance Mode | Recessive |
Strain of Origin | mixed | Is Recombinase | false |
Is Wild Type | false |
description | Mutation arose from mixed C57BL/6, BALB/c, C3H, and 129/Sv parentage. |
molecularNote | An A-to-G mutation at coding nucleotide 1165 resulted in an arginine to glycine substitution at amino acid position 389 (p.R389G). This mutation is within the second of four zinc finger domains and affects a residue predicted to interact directly with DNA. |