| Primary Identifier | MGI:1914203 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 66953 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of cell population proliferation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 3. Orthologous to human CDCA7 (cell division cycle associated 7). PHENOTYPE: Homozygosity for the p.G305V mutation reduces global DNA methylation levels and affects expression of various genes and gene clusters. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
