Type | MGI:General | Description | opacities and lens tissue destruction were apparent in the nucleus of the lens at three weeks of age by both slit-lamp and histological analyses increasing incidence and severity with age noted at 8 weeks of age compared to 3 weeks of age; as cataract formation progressed, both the opacities and the region of tissue destruction were observed to spread towards the cortex of the lens variable penetrance; more severe on this inbred genetic background than on a mixed genetic background more severe than heterozygote |