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Protein Domain : Toxin co-regulated pilus biosynthesis protein Q, C-terminal

Primary Identifier  IPR018927 Type  Domain
Short Name  Pilus_synth_Q_C
description  The toxin-coregulated pilus (TCP) of Vibrio cholerae and the soluble TcpF protein that is secreted via the TCP biogenesis apparatus are essential for intestinal colonisation in the disease of cholera. TCP fibres are homopolymers of TcpA pilin, encoded by the first gene in the tcp biogenesis operon. TcpQ is part of an outer membrane complex of the TCP biogenesis apparatus, comprised of TcpC and TcpQ. TcpQ is required for proper localisation of TcpC to the outer membrane [, ]. This entry represents a C-terminal domain found in TcpQ and other pilus biosynthesis proteins.

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