First Author | McKnight AJ | Year | 1996 |
Journal | Immunol Today | Volume | 17 |
Issue | 6 | Pages | 283-7 |
PubMed ID | 8962632 | Mgi Jnum | J:33476 |
Mgi Id | MGI:80955 | Doi | 10.1016/0167-5699(96)80546-9 |
Citation | McKnight AJ, et al. (1996) EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules. Immunol Today 17(6):283-7 |
abstractText | The recent cDNA cloning of three cell-surface molecules has identified a subfamily of leukocyte proteins that are characterized by the presence of tandemly repeated extracellular epidermal growth factor (EGF)-like domains and a seven-transmembrane (Tm7) region. Here, Andrew McKnight and Siamon Gordon review the unusual structural propeties of these molecules, their similarities to certain peptidic hormone receptors, and speculate as to their immunological function. |