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Allele : Arhgef28<tm1.1Ddsr> Rho guanine nucleotide exchange factor 28; targeted mutation 1.1, David D Schlaepfer
Primary Identifier  MGI:5638671 Allele Type  Targeted
Attribute String  Null/knockout Gene  Arhgef28
Transmission  Germline Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette was inserted upstream of exon 24. An additional loxP site was inserted downstream of exon 24. Cre-mediated recombinated removed the selection cassette and exon 24. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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