Primary Identifier | MGI:1352501 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 29815 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable kinase binding activity and phosphotyrosine residue binding activity. Acts upstream of or within lens morphogenesis in camera-type eye and positive regulation of peptidyl-serine phosphorylation. Located in focal adhesion and membrane. Is expressed in brain; retina; submandibular gland primordium; testis; and tongue epithelium. Orthologous to human BCAR3 (BCAR3 adaptor protein, NSP family member). PHENOTYPE: Mice homozygous for a knock-out allele exhibit cataracts due to rupture of the lens capsule and liquefaction of lens cortical fibers. [provided by MGI curators] |