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Allele : Tcrb<tm2Slek> T cell receptor beta chain; targeted mutation 2, Barry P Sleckman

Primary Identifier  MGI:3702574 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tcrb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  ES cells containing Tcrbtm1Slek, which contain a loxP site in place of the Dbeta2-Jbeta2 gene cluster, were additionally targeted to replace the 5' Dbeta1 12-RSS with the Jbeta1.2 12-RSS. The allele also contains loxP and HindIII sites between Dbeta1 and Jbeta1.1, as well as the conversion of a bamHI site 3' of Jbeta1.2 to a PstI site. A floxed neo cassette was removed from the locus.
  • mutations:
  • Insertion
  • synonyms:
  • Jbeta1<M4>,
  • Jbeta1<M4>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele