Primary Identifier | MGI:5804590 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Camkmt |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A beta-gal and floxed neomycin resistance cassette replaced the first exon and part of the first intron. This mutation corresponds to the border of the deletion in patients with 2p21 deletion syndrome. Western blot analysis confirmed the absence of protein expression in liver and kidney. |