First Author | Schumacker PT | Year | 2015 |
Journal | Cancer Cell | Volume | 27 |
Issue | 2 | Pages | 156-7 |
PubMed ID | 25670075 | Mgi Jnum | J:219950 |
Mgi Id | MGI:5630015 | Doi | 10.1016/j.ccell.2015.01.007 |
Citation | Schumacker PT (2015) Reactive oxygen species in cancer: a dance with the devil. Cancer Cell 27(2):156-7 |
abstractText | Reactive oxygen species (ROS) can initiate cancer, but oxidant generation in tumors leaves them vulnerable to further stresses. In this issue of Cancer Cell, Harris and colleagues show that augmenting oxidant stress in normal cells limits tumor initiation and progression. Hence, strategic targeting of antioxidant systems may undermine survival of new tumor cells. |