Primary Identifier | MGI:1349660 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 26970 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium-dependent phospholipase A2 activity. Involved in phosphatidylcholine metabolic process and phosphatidylglycerol metabolic process. Acts upstream of or within low-density lipoprotein particle remodeling. Located in extracellular region. Is expressed in several structures, including alimentary system; cranium; heart; respiratory system; and telencephalon. Orthologous to human PLA2G2E (phospholipase A2 group IIE). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal IgE antigen-dependent passive cutaneous anaphylaxis. [provided by MGI curators] |