| First Author | Berger FG | Year | 1978 |
| Journal | J Biol Chem | Volume | 253 |
| Issue | 15 | Pages | 5280-2 |
| PubMed ID | 97289 | Mgi Jnum | J:6006 |
| Mgi Id | MGI:54483 | Doi | 10.1016/s0021-9258(17)30366-6 |
| Citation | Berger FG, et al. (1978) Regulation of the rate of beta-galactosidase synthese by the Bgs and Bgt loci in the mouse. J Biol Chem 253(15):5280-2 |
| abstractText | We have developed an assay for the in vivo rate of beta-galactosidase synthesis in mouse tissues to assess the mechanism by which the Bgs and Bgt loci regulate activity levels of this enzyme. Genetically determined differences in liver and kidney beta-galactosidase content reflect equivalent differences in specific rates of enzyme synthesis. We conclude that Bgs and Bgt regulate beta-galactosidase activity by controlling the rate of synthesis of the beta-galactosidase molecule. |
