| Primary Identifier | MGI:2442819 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 243931 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Predicted to enable DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and chromatin binding activity. Involved in several processes, including positive regulation of synaptic transmission; regulation of respiratory gaseous exchange by nervous system process; and smooth muscle tissue development. Acts upstream of or within several processes, including kidney development; positive regulation of smooth muscle cell differentiation; and sensory perception of touch. Located in mitochondrion. Is expressed in genitourinary system and peripheral nervous system. Used to study autism spectrum disorder. Orthologous to human TSHZ3 (teashirt zinc finger homeobox 3). PHENOTYPE: Mice homozygous for a null allele exhibit neoatal lethality likely due to respiratory distress and hydroureter and hydronephrosis associated with impaired development of ureteric smooth muscle. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
