Primary Identifier | MGI:1921248 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 73998 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Is expressed in embryo mesenchyme; esophagus; lung; nervous system; and sensory organ. Orthologous to human HERC3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3). PHENOTYPE: Mice homozygous for a null allele exhibit abnormal hair follicle bulge morphology. [provided by MGI curators] |