Primary Identifier | MGI:5911101 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(ACTB-Wld)4858Cole |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A construct consisting of the human beta actin promoter followed by the cDNA for Wlds that is an in-frame fusion of exon 1 and 2 of Ube4b to exon 2 onwards of Nmnat1, was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs that do not express Wlds. Expression level of this transgene is lower than that of Wlds in the C57Bl/6Ola strain. |