| First Author | Gläser B | Year | 1998 |
| Journal | Mamm Genome | Volume | 9 |
| Issue | 3 | Pages | 226-31 |
| PubMed ID | 9501307 | Mgi Jnum | J:46259 |
| Mgi Id | MGI:1197423 | Doi | 10.1007/s003359900730 |
| Citation | Glaser B, et al. (1998) Simian Y chromosomes: species-specific rearrangements of DAZ, RBM, and TSPY versus contiguity of PAR and SRY. Mamm Genome 9(3):226-31 |
| abstractText | The three human male specific expressed gene families DAZ, RBM, and TSPY are known to be repetitively clustered in the Y-specific region of the human Y Chromosome (Chr). RBM and TSPY are Y-specifically conserved in simians, whereas DAZ cannot be detected on the Y chromosomes of New World monkeys. The proximity of SRY to the pseudoautosomal region (PAR) is highly conserved and thus most effectively stabilizes the pseudoautosomal boundary on the Y (PABY) in simians. In contrast, the non-recombining part of the Y Chrs, including DAZ, RBM, and TSPY, was exposed to species-specific amplifications, diversifications, and rearrangements. Evolutionary fast fixation of any of these variations was possible as long as they did not interfere with male fertility. |
