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Protein Coding Gene : Otub1 OTU domain, ubiquitin aldehyde binding 1

Primary Identifier  MGI:2147616 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  107260
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including ubiquitin protein ligase binding activity; ubiquitin-like protein peptidase activity; and ubiquitin-protein transferase inhibitor activity. Predicted to be involved in DNA damage response; negative regulation of double-strand break repair; and positive regulation of TORC1 signaling. Predicted to act upstream of or within DNA repair; adaptive immune response; and proteolysis. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; connective tissue; genitourinary system; and sensory organ. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1).
PHENOTYPE: Mice homozygous for a null allele die between E14.5 and birth. [provided by MGI curators]
  • synonyms:
  • Otub1,
  • OTU domain, ubiquitin aldehyde binding 1,
  • expressed sequence AI850305,
  • AI850305

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For