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Protein Coding Gene : Olfm4 olfactomedin 4
Primary Identifier  MGI:2685142 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  380924
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cadherin binding activity and structural molecule activity. Acts upstream of or within negative regulation of canonical NF-kappaB signal transduction and negative regulation of immune response. Located in extracellular space. Is expressed in bone marrow; colon; intestine; metanephros; and small intestine. Orthologous to human OLFM4 (olfactomedin 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced colonization of the gastric mucosa by Helicobacter pylori but increased inflammatory response to H. pylori infection. [provided by MGI curators]
  • synonyms:
  • gene model 913, (NCBI),
  • Olfm4,
  • gene model 296, (NCBI),
  • GC1,
  • pPD4,
  • GW112,
  • olfactomedin 4,
  • OlfD,
  • LOC239192,
  • Gm296,
  • Gm913,
  • LOC380924,
  • MGI:2685759
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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1 Driver For

Trail: ProteinCodingGene




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