| Primary Identifier | MGI:1933206 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 242443 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables NMDA glutamate receptor activity; calcium channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including chemical postsynaptic transmission; dendrite development; and prepulse inhibition. Located in neuronal cell body and postsynaptic membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; foot bone; and hand mesenchyme. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A). PHENOTYPE: Mice homozygous for a disruption in this gene display increased current densities in some cerebrocortical neurons of the brain, increased levels of prepulse inhibition, and altered dendritic spine morphology. Otherwise, they display a normal phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
