Primary Identifier | MGI:4456121 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Trp53 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site flanked neomycin resistance gene cassette and a human gene fragment containing an amino acid substitution of arginine with histidine at position 175 (p.R175H) replaced exon 4 through 9. The neo cassette was removed by Cre-mediated recombination. |