Primary Identifier | MGI:3522719 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Upk2-HRAS*Q61L)5Xrw |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene included a 3.6 kb fragment encoding the muring Upk2 gene promoter placed upstream of a 3.0 kb sequence encoding a mutant rabbit Hras gene (glutamine to leucine point mutation at codon 61). Mice carrying this allele produced only a single fragment, 8.2 kb in length, corresponding to a tail to tail orientation. Approximately 2 copies of the transgene were inserted into the genome. |