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Allele : Sik2<tm1.1Mfor> salt inducible kinase 2; targeted mutation 1.1, Marc Foretz

Primary Identifier  MGI:5905012 Allele Type  Targeted
Attribute String  Conditional ready Gene  Sik2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  An frt site flanked hygromycin resistance gene cassette was inserted in intron 4. Exon 5 was flanked by loxP sites. Exon 5 codes for part of the active catalytic domain including the Thr175 phosphorylation site within the activation loop. The hygro cassette was removed through subsequent FLP-mediated recombination, leaving a conditional-ready allele with a floxed exon 5.
  • mutations:
  • Insertion
  • synonyms:
  • SIK2<lox>,
  • SIK2<lox>,
  • SIK2<lox>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele