Primary Identifier | MGI:2384134 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Id2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.2 kb region of the gene including the promoter and an exon was replaced with a PGK-neo cassette via homologous recombination. Northern blot analysis using the full cDNA sequence as a probe demonstrated the absence of gene expression in liver from homozygous mutant animals. |