Primary Identifier | MGI:5567929 | Allele Type | Targeted |
Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | BALB/c |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct introduced into the locus a floxed neomycin resistance/stop cassette and a fusion of the EBV B95-8 strain Lmp1 coding sequence encoding amino acids 1-190 and the human cDNA encoding amino acids 223-280. This fusion generates a constitutively active receptor that is only expressed after cre-mediated removal of the stop cassette. |