| First Author | Hedgepeth CM | Year | 1999 |
| Journal | Mech Dev | Volume | 80 |
| Issue | 2 | Pages | 147-51 |
| PubMed ID | 10072781 | Mgi Jnum | J:53541 |
| Mgi Id | MGI:1332912 | Doi | 10.1016/s0925-4773(98)00203-2 |
| Citation | Hedgepeth CM, et al. (1999) Xenopus axin interacts with glycogen synthase kinase-3 beta and is expressed in the anterior midbrain. Mech Dev 80(2):147-51 |
| abstractText | Axin is encoded by the fused locus in mice and is required for normal vertebrate axis formation. It has recently been shown that axin associates with APC, beta-catenin and glycogen synthase kinase-3 (GSK-3) in a complex that appears to regulate the level of cytoplasmic beta-catenin. We have identified the Xenopus homologue of axin through its interaction with GSK-3b. Xenopus axin (Xaxin) is expressed maternally and throughout early development with a low level of ubiquitous expression. Xaxin also shows remarkably high expression in the anterior mesencephalon adjacent to the forebrain-midbrain boundary. Copyright 1998 Elsevier Science Ireland Ltd. |
