Primary Identifier | MGI:5569304 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dcbld2 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 1. A floxed neomycin resistance cassette was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the selection cassette. Western blot analysis and flow cytometry confirmed the absence of protein expression in murine lung endothelial cells. |