Primary Identifier | MGI:1917458 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 70208 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within positive regulation of T cell extravasation and positive regulation of gene expression. Part of mediator complex. Is expressed in several structures, including genitourinary system. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Orthologous to human MED23 (mediator complex subunit 23). PHENOTYPE: Homozygous null mice display embryonic lethality during organogenesis with disorganization of the vasculature and peripheral nervous system. [provided by MGI curators] |