| Primary Identifier | MGI:1330841 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 12049 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in microtubule organizing center organization. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of intrinsic apoptotic signaling pathway; and positive regulation of apoptotic process. Located in membrane and spindle. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system; liver; and meninges. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). PHENOTYPE: Mice homozygous for a targeted mutation exhibit no obvious abnormalities. They are viable and fertile with normal reproductive capacity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
