Primary Identifier | MGI:1929760 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 56699 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity. Acts upstream of or within Rho protein signal transduction and cellular response to type II interferon. Located in phagocytic vesicle. Is expressed in several structures, including central nervous system; forelimb bud; heart valve; lung; and retina. Orthologous to human CDC42EP4 (CDC42 effector protein 4). PHENOTYPE: Mice homozygous for a null allele display impaired glutamate clearance and motor learning. [provided by MGI curators] |