| Primary Identifier | MGI:1931553 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 104215 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GBD domain binding activity; GTP binding activity; and profilin binding activity. Involved in cellular response to insulin stimulus; cortical actin cytoskeleton organization; and negative regulation of protein localization to plasma membrane. Acts upstream of or within regulation of cell shape. Located in membrane raft. Is expressed in dentate gyrus subgranular zone; lower leg bone; and telencephalon. Orthologous to human RHOQ (ras homolog family member Q). PHENOTYPE: Mice homozygous for a null allele exhibit normal brain development but show reduced axon regeneration after injury in both the peripheral and central nervous systems. Cultured hippocampal neurons display reduced axon elongation without affecting polarization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
