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Allele : Tnf<tm1Sek> tumor necrosis factor; targeted mutation 1, Kenji Sekikawa
Primary Identifier  MGI:2653694 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnf
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  All of exon 3 and a portion of exon 4 were replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the DNA-binding domain (aa 84 through 174).
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • TNF-alpha-,
  • TNF-alpha-,
  • TNFalpha KO,
  • TNFalpha KO,
  • TNF-,
  • TNFalpha<->,
  • TNF-,
  • TNFalpha<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

69 Publication categories

Trail: Allele




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