| Primary Identifier | MGI:2385833 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Vpreb1b |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cells heterozygous for Vpreb1tm1Ilm were electroporated with the targeting vector. Two targeted mutant lines identified as ES94 and as ES163 were interbred to create this mutant lineage. This allele always exists in association with Vpreb1tm1Ilm. |
| molecularNote | A single copy of a construct in which the entire coding region was replaced with a hygromycin cassette was incorporated at the endogenous locus via homologous recombination. Transcript was undetected by RT-PCR analysis of bone marrow cells obtained from homozygous mutant mice. The absence of protein surface expression was confirmed by FACS analysis. |
