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Allele : Cxcl13<tm1Cys> C-X-C motif chemokine ligand 13; targeted mutation 1, Jason G Cyster

Primary Identifier  MGI:2384500 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cxcl13
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Base pairs 18 through 116 (exon 2) were replaced by a cassette containing a stop codon followed by an internal ribosome entry site, an enhanced green fluorescent protein gene, and a floxed neo gene. The deleted region encoded amino acids 27 through 60, including 3 of the 4 conserved Cys residues. The absence of transcript and protein in homozygous mutant mice was confirmed by Northern and Western blot analyses of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CXCL13<->,
  • BLC<->,
  • BLC<->,
  • CXCL13<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

35 Publication categories