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Protein Coding Gene : Kat14 lysine acetyltransferase 14

Primary Identifier  MGI:1917264 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  228714
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone acetyltransferase activity. Involved in regulation of cell cycle; regulation of cell division; and regulation of embryonic development. Acts upstream of or within G2/M transition of mitotic cell cycle. Located in nucleus. Part of ATAC complex. Is expressed in embryo and extraembryonic component. Orthologous to human KAT14 (lysine acetyltransferase 14).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis, decreased size, increased apoptosis, and disrupted cell cycling. Mice heterozygous for one targeted allele exhibit corneal opacity. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2510008M08 gene,
  • MGI:107351,
  • AU023459,
  • DNA segment, Chr 2, Wayne State University 131, expressed,
  • D2Ertd473e,
  • Csrp2bp,
  • DNA segment, Chr 2, ERATO Doi 473, expressed,
  • MGI:1196394,
  • MGI:2139204,
  • D2Wsu131e,
  • 2510008M08Rik,
  • Kat14,
  • MGD-MRK-35817,
  • expressed sequence AU023459,
  • ATAC2,
  • lysine acetyltransferase 14,
  • cysteine and glycine-rich protein 2 binding protein

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For