Type | MGI:General | Description | when this allele is paternally inherited a 1.6- to 1.8-fold increase in apoptosis is seen in the cervical dorsal root ganglia at E12.5 the density of nociceptive neurons (substance P-containing) is reduced to 59% that in wild-type mice at P0 at P0 the total neuron number is reduced to 88% that in wild-type mice |