Primary Identifier | IPR012777 | Type | Family |
Short Name | LTA4H |
description | Members of this family represent a distinctive subset within the zinc metallopeptidases of MEROPS peptidase family M1 (aminopeptidase N, clan MA). This entry represents leukotriene A-4 hydrolase (LTA4), which in vertebrates has both epoxide hydrolase and aminopeptidase activity at the same active site []. In contrast, highly homologous enzymes from yeast only have the aminopeptidase activity, showing low epoxide hydrolase activity in vitro. This is the case for leucine aminopeptidase LTA4H from budding yeast []. |