Primary Identifier | MGI:4362083 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Was |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An frt and loxP flanked neo cassette was inserted downstream of exon 7. Exon 9 was replaced with one in which nucleotide substitution (TAC->GAA) results in the amino acid substitution of glutamic acid for tyrosine at position 293 (Y293E). This allele contains a phosphomimicking mutation. |