| First Author | Konoshima T | Year | 1999 |
| Journal | Biol Pharm Bull | Volume | 22 |
| Issue | 10 | Pages | 1150-2 |
| PubMed ID | 10549877 | Mgi Jnum | J:59556 |
| Mgi Id | MGI:1351792 | Doi | 10.1248/bpb.22.1150 |
| Citation | Konoshima T, et al. (1999) Anti-carcinogenic activity of the roots of Panax notoginseng. II. Biol Pharm Bull 22(10):1150-2 |
| abstractText | The extract of the roots of Panax notoginseng (Araliaceae) exhibited a significant anti-tumor-promoting activity on two-stage carcinogenesis of mouse skin tumors induced by 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and a mycotoxin, fumonisin B1, as a non-12-O-tetradecanoylphorbol-13-acetate (non-TPA) type promoter. Further, the extract exhibited the anti-tumor-initiating activity on two-stage carcinogenesis of mouse skin tumors induced by a nitric oxide donor, (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexen amide (NOR-1) as an initiator and TPA as a promoter. |
