| Primary Identifier | MGI:3042130 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Ace |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| description | J:163454 selected for the single renin gene locus found in C57BL/6 mice instead of the duplicated locus found in 129 mice. |
| molecularNote | An allele carrying point mutations H395K and H399K in exon 8 was inserted via homologous recombination. Inactivation of the N-terminal catalytic site was confirmed using an N-terminal specific substrate. Expression of the mutant protein was shown to be equivalent to expression of the normal protein by western blot analysis. |
