Primary Identifier | MGI:5320879 | Allele Type | Targeted |
Gene | Igh | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The Mbalpha exon (Calpha membrane exon) was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. ELISA analysis confirmed the reduction in IgA protein expression. |