| Primary Identifier | MGI:2661136 | Allele Type | Targeted |
| Attribute String | Modified isoform(s), Reporter | Gene | Rtn4 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The coding region of exon 1, which is specific to isoforms A and B (but not to isoform C), was replaced with a cassette containing IRES-GFPLacZ-loxP and an frt flanked hprt. Northern blot analysis of homozygous mutant brain tissue indicated an absence of A and B transcript and confirmed the presence of C transcript. The A and B isoforms were undetected by Western blot analysis. |
