| Primary Identifier | MGI:2442675 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 319758 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in positive regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human RFX7 (regulatory factor X7). PHENOTYPE: Mice homozygous for a null allele exhibit incomplete preweaning lethality. Mice homozygous for a null allele activated in hematopoietic cells exhibit decreased NK cell maintenance and immunity in vivo and increased NK cell size, granularity, proliferation, and energetic state. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
