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Protein Domain : Rho guanine nucleotide exchange factor 25

Primary Identifier  IPR030738 Type  Family
Short Name  ARHGEF25
description  Rho guanine nucleotide exchange factor 25 (ARHGEF25, GEFT), also known as p63RhoGEF, is a RhoA-specific guanine nucleotide exchange factor. It is found in vascular smooth muscle (SM) and may play a role in selective targetingof RhoA-mediated regulation of basal blood pressure through agonists that couple through G alpha(q/11) [, ]. It is thought to be involved in muscle regeneration, myogenesis, and adipogenesis regulation by modulating mesenchymal cell fate decisions [].

0 Child Features

0 Parent Features

8 Protein Domain Regions