| Primary Identifier | MGI:87984 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 11648 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable alkaline phosphatase activity; metal ion binding activity; and protease binding activity. Acts upstream of or within neural tube development; neurogenesis; and post-anal tail morphogenesis. Located in brush border. Is expressed in duodenum; intestine; and jejunum. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to human ALPG (alkaline phosphatase, germ cell) and ALPI (alkaline phosphatase, intestinal). PHENOTYPE: Mice homozygous for disruption of this gene show no gross abnormalities in appearance, behavior or fertility. They do display accelerated lipid absorption on a high fat diet leading to elevated plasma triglycerides and increased weight gain. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
