First Author | Waymouth C | Year | 1983 |
Journal | J Natl Cancer Inst | Volume | 70 |
Issue | 1 | Pages | 199-208 |
PubMed ID | 6571915 | Mgi Jnum | J:35930 |
Mgi Id | MGI:83373 | Citation | Waymouth C, et al. (1983) Spontaneous tumors of the prostate gland in inbred strains of mice. J Natl Cancer Inst 70(1):199-208 |
abstractText | Spontaneous tumors of the prostate gland in the house mouse (Mus musculus) have rarely been described. In a histologic survey of prostate glands from old (greater than 700 days of age) mice, we have observed 2 primary adenocarcinomas of the prostate gland, 1 in a 1,047-day-old C57BL/6J mouse (DEH 1009) and 1 with metastases to the kidney and lungs in a 778-day-old C57BL/KsJ mouse (DEH 705C). We have also found a rhabdomyosarcoma of the prostate gland in a C57BL/6J mouse (DEH 1121C) 732 days old. The histologic characteristics of these tumors, and of the prostate glands of mice of similar ages without prostatic neoplastic involvement, including a 736-day-old CBA/CaJ mouse (DEH 849) with adenomatous hyperplasia, are described. |