Primary Identifier | MGI:3512173 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Grin3b |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1, which contains the initiation codon and sequences encoding the signal peptide, was replaced with a loxP-flanked neomycin selection cassette. The selection cassette was removed through Cre-mediated recombination, leaving a single loxP site in place of exon 1. RT-PCR and in situ hybridization analysis confirmed that no detectable transcript is expressed from this allele. |