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Protein Domain : Sin3, C-terminal

Primary Identifier  IPR031693 Type  Domain
Short Name  Sin3_C
description  This entry represents a domain found in the C-terminal of the transcriptional repressor Sin3.Budding yeast Sin3 is a component of both the Rpd3S and Rpd3L histone deacetylase complexes []. In mammals there are two Sin3 paraologues, Sin3A and Sin3B. They forms the larger Sin3L/Rpd3L and the smaller Sin3S/Rpd3S complexes, both complexes rely largely on HDAC (histone deacetylase) activity to affect transcriptional repression. Sin3A and Sin3B may partition into the Sin3L/Rpd3L and Sin3S/Rpd3S complexes, respectively [].

0 Child Features

0 Parent Features

4 Protein Domain Regions