|  Help  |  About  |  Contact Us

Allele : Gt(ROSA)26Sor<tm1(ITK/SYK)Jrld> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jurgen Ruland

Primary Identifier  MGI:4460818 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA for the fusion of human ITK-SYK, which is preceded by a splice acceptor and floxed neo cassette and followed by an IRES-eGFP and polyadenylation sequence, was inserted into the locus. Cre mediated recombination is required to induce expression of the fusion cDNA. This fusion was identified peripheral T cell lymphoma patients with the chromosomal translocation t(5;9)(q33;p22).
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26<loxSTOPlox-ITK-SYK>,
  • Rosa26<loxSTOPlox-ITK-SYK>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele