| Primary Identifier | IPR001862 | Type | Family |
| Short Name | MAC_perforin |
| description | Complement component C9 is a multi-domain protein that contains anN-terminal type-1 TSP domain, an LDL-receptor class A repeat, a number ofpotential transmembrane (TM) regions and a C-terminal EGF-like domain [, , ]. Hydropathy analysis of the sequence indicates the N-terminal half of C9 to be predominantly hydrophilic in character, while the C-terminal section is more hydrophobic. The amphipathic organisation of the primary structureis consistent with the known potential of polymerised C9 to penetrate lipidbilayers, causing the formation of transmembrane channels [, ] |
