| Primary Identifier | MGI:2152826 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ryr1 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette was inserted into exon 2 which encodes amino acids 18-58. Northern blot and RT-PCR analysis on RNA derived from skeletal muscle detected a larger transcript in homozygous mice than in wild-type. Western blot analysis confirmed that no full length protein is expressed from this allele. |
